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Enzyme catalyzes many reactions: plants

Many plants and microorganisms can catalyze a wide variety of organic chemical reactions via the 2OG oxygenase enzyme.

"In plants and microorganisms…2OG oxygenases catalyze a plethora of oxidative reactions, which has led to the proposal that they may be the most versatile of all oxidizing biological catalysts. Some of these reactions are chemically remarkable and indeed presently cannot be achieved through synthetic—that is, non-biological—chemistry. Oxidative reactions catalyzed by 2OG oxygenases include cyclizations, ring fragmentation, C-C bond cleavage, epimerization, desaturation and the hydroxylation of aromatic rings. The discovery that 2OG oxygenases can catalyze chlorination reactions further extends the scope of the family." (Flashman 2007:86)
About the inspiring organism

Learn more at
Organism/taxonomy data provided by:
Species 2000 & ITIS Catalogue of Life: 2008 Annual Checklist

Bioinspired products and application ideas

Application Ideas: Develop a common process for manufacturing a wide variety of organic compounds, thereby reducing waste streams.

Industrial Sector(s) interested in this strategy: Organic chemical manufacture

Schofield Group
Christopher J. Schofield
Chemistry Research Laboratory, Oxford University
Flashman, Emily; Schofield, Christopher J. 2007. The most versatile of all reactive intermediates?. Nat Chem Biol. 3(2): 86-87.
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over 4 years ago
Has anybody ever looked at how to harness the power of the plant Heracleum mantegazzianum (Hog Weed)? The sap in giant hogweed is clear and watery, but it contains toxins that cause photo-dermatitis, a skin reaction to ultraviolet rays. As a result, skin that comes in contact with the sap and is then exposed to sunlight will blister and burn — injuries that can lead to long-lasting skin discoloration and scars. Is this a power worth looking into?

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