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Toxin breaks down tissue: Mycobacterium ulcerans


The mycolactone toxin produced by Mycobacterium ulcerans effectively causes local cell or tissue death because it is immunosuppressive and cytotoxic.

Biomimetic Application Ideas
 
Understanding the immunosuppressive and cytotoxic properties of the mycolactone toxin; treatment for tumors.


[Collapse all sections] Summary
Spiders that live in soil in Australia are vectors for Mycobacterium ulcerans, a bacterium that can cause large, expanding areas of necrosis when it infects a flesh wound. (Shuker 2001:120-121)
About the inspiring organism
Mycobacterium ulcerans
Mycobacterium ulcerans MacCallum et al. 1950 (Approved Lists 1980)


Some organism data provided by: BIOS: Bacteriology Insight Orienting System
Organism/taxonomy data provided by:
Species 2000 & ITIS Catalogue of Life: 2008 Annual Checklist

Bioinspired products and application ideas

Application Ideas: Understanding the immunosuppressive and cytotoxic properties of the mycolactone toxin; treatment for tumors.

Industrial Sector(s) interested in this strategy: Medical

References
Shuker, KPN. 2001. The Hidden Powers of Animals: Uncovering the Secrets of Nature. London: Marshall Editions Ltd. 240 p.
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