• Strategy

Bones self-heal: vertebrates


Horses running / Greg Robbins / LicenseCC-by-nc-sa - Attribution Non-commercial Share Alike

Osteoclasts/osteoblasts of bones maintain skeletal homeostasis by resorbing bone/forming newly synthesized matrix.

"Bone remodeling is the result of the coordinated activity of osteoblasts, which form new matrix, and osteoclasts, which resorb bone…Bone remodeling is a temporally and spatially regulated process that results in the coordinated resorption and formation of skeletal tissue (1). Bone remodeling is carried out in basic multicellular units in which osteoclasts resorb bone and osteoblasts form newly synthesized matrix in a coordinated process that takes about 4 months…The number and function of osteoclasts and osteoblasts are regulated by extracellular and intracellular signals acting in a coordinated fashion to maintain skeletal homeostasis." (Canalis 2008:1)

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About the inspiring organism

Learn more at EOL.org
Organism/taxonomy data provided by:
Species 2000 & ITIS Catalogue of Life: 2008 Annual Checklist

Bioinspired products and application ideas

Application Ideas: Self-healing material such as concrete and ceramics. Building materials that adjust to internal and external stresses by adding or removing material as needed. Creating lightweight, yet strong materials by taking away unneeded material and adding material where stresses are greatest.

Industrial Sector(s) interested in this strategy: Construction, manufacturing

Department of Research
Ernesto Canalis
Saint Francis Hospital and Medical Center
Canalis, E. 2008. Notch Signaling in Osteoblasts. Science Signaling. 1(17):
Learn More at Google Scholar Google Scholar  


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over 7 years ago
The You Tube Video has some great images - would be great to ask permission to make a slide show version - images and text - that could be used in this site. Great visual reference as inspiration for design.
over 7 years ago
Where do I find the information on the strategy?
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